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Profile of Magic_son
Within the last year I have experienced two different incidents where bone strengthening medicine had an adverse effect due to the length of time the person has been on them. In both cases, one being my a fellow employee and one being my mother, the fibula has broken.
This may not be the case with every single person, but if you either know someone or have a loved one on this type of medicine, please have them check with a endocrinologist to check. My mother was 81 when this happened, standing at the stove. As she turned the bone snapped. Both my mother and the other lady had been on this medicine for about 15 years.
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Profile of landmark
Sorry to hear that, Magic_son. I hope your mother and her friend recover soon. The list of warning and side effects on that drug is truly awesome:

"You should check with your doctor immediately if any of these side effects occur when taking ibandronate:
More common

Bladder pain
bloody or cloudy urine
chest pain
cough producing mucus
difficult, burning, or painful urination
difficulty with breathing
fever or chills
frequent urge to urinate
lower back or side pain
pounding in the ears
shortness of breath
slow or fast heartbeat
sore throat
tightness in the chest

Less common

Bloody or cloudy urine
body aches or pain
difficulty with swallowing
dryness of the throat
fast heartbeat
frequent urge to urinate
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
runny nose
skin rash
tender, swollen glands in the neck
unusual tiredness or weakness
voice changes

Incidence not known

Abdominal or stomach cramps
blurred vision or other change in vision
bone, joint, or muscle pain, severe and occasionally incapacitating
eye redness
eye tenderness
heavy jaw feeling
irregular heartbeats
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
loosening of a tooth
muscle cramps in the hands, arms, feet, legs, or face
noisy breathing
numbness and tingling around the mouth, fingertips, or feet
pain, swelling, or numbness in the mouth or jaw
sensitivity to light
severe eye pain
unusual pain in the thighs, groin, or hips

If any of the following symptoms of overdose occur while taking ibandronate, get emergency help immediately:
Symptoms of overdose

Acid or sour stomach
bone pain
burning feeling in the chest or stomach
loss of appetite
pain or burning in the throat
sores or ulcers
stomach discomfort, upset, or pain
tenderness in the stomach area
white spots on the lips or tongue or inside the mouth

Some of the side effects that can occur with ibandronate may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
More common

ear congestion
loss of voice
pain in the extremity (arms and legs)

Less common

difficulty having a bowel movement (stool)
difficulty with moving
feeling of constant movement of self or surroundings
feeling sad or empty
general feeling of discomfort or illness
joint pain
lack or loss of strength
loss of interest or pleasure
muscle aches and pain
muscle stiffness
pain, swelling, or redness in the joints
sensation of spinning
stuffy nose
tooth disorder
trouble concentrating
trouble sleeping"
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